Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1000 | Growth hormone IGF axis - basic | ICEECE2012

Anti-androgen flutamide alters gene expression in the porcine fetal ovary

Knapczyk-Stwora K. , Durlej M. , Duda M. , Galas J. , Koziorowski M. , Slomczynska M.

In pigs, the assembly of primordial follicles and their subsequent transition to the primary stage occur in the late gestational and neonatal period. Previously, we reported the presence of androgen receptors in the porcine fetal ovary on different days of gestation, which suggests a fetus capacity to respond to androgens. Since testosterone was detected in the plasma of porcine female fetuses during the second half of pregnancy, it is possible that androgens are involved in p...